Review of Research Paper on Parkinsons Disease Treatment

AbstractAttempts to cure or slow down the progression of Parkinsons disease have largely failed researchers in this paper maintain this is obviously a direct result of the lack of insight into the pathogenesis of the disease. Parkinsons disease is the product of the deaths of a number of dopaminergic (dopamine-secreting) neurons in the substantia nigga pars compacta region (SNc) of the brain. But what causes these deaths? In the paper Rejuvenation protects neurons in mouse models of Parkinsons disease, Chen and researchers find that older neurons in the SNc are unusually dependent on calcium channels and that after blocking these channels, the cells are rejuvenated and begin acting like their juvenile counterparts as a result, these cells become protected from Parkinsons disease. Their research, thus, points not only to a possible cause of neuronal death in PD but also to a possible means of set the disease. Causes / Risk Factors Genetics15-25% of people who have the disease h ave a parent with the disease. Having a parent with the disease increases a persons risk by 3 fold.There has not been enough research done on the genetic causes of Parkinsons Disease to say for a fact that they are directly correlated. When much research is done there may be more strong evidence, but it could go the complete other way as well. The Human Genome throw should open many doors with the research of this disease once the funding is sufficient. Environmental factorsAccording to the Parkinsons Disease Foundation, Epidemiological research has identified several factors that may be linked to PD, including rural living, well water, herbicide use and exposure to pesticides. They also state that a narc... ....org/AboutPD/causes.cfmMayo Clinic Staff, Parkinsons Disease. Nervous System. 12 004 2007. Mayo Clinic. 1 Nov 2007 .Melanie, Brandabur. Complementary and Alternative Medicine and Parkinson Disease. National Parkinson Foundation. 1 Nov 2007 .Parkinsons Disease. MayoClinic. com. 12 April 2007. Mayo Foundation for Medical Education and Research. 15 Nov. 2007. .Parkinsons Disease. Wikipedia The Free Encyclopedia. 9 Nov. 2007. Wikimedia Foundation, Inc. 15 Nov. 2007. .What Causes Parkinsons Disease. 2007. Parkinsons Disease Foundation. 1 Nov 2007 .